منابع مشابه
Vitamin C revisited
This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show that high-dose vitamin C can prevent or restore microcirculatory flow impairment by inhibiting activation of nicotinamide adenine dinucleotide phosphate-oxidase and inducible nitric oxid...
متن کاملVitamin C and cancer revisited.
I n this issue of PNAS, Chen et al. (1) show that i.p. injection of ‘‘pharmacologic doses’’ of vitamin C decreases the growth and weight of human, rat, and murine tumor xenografts in athymic, nude mice. This work follows a number of articles by the same group, led by Mark Levine at the National Institute of Diabetes and Digestive and Kidney Diseases, showing that millimolar concentrations of ex...
متن کاملVitamin C and Oxidative DNA Damage Revisited
Reactive oxygen metabolites can pro mote carcinogenesis by damaging DNA. vi tamin C is a redox chemical with antioxi dant and pro-oxidant properties that may produce radical species depending on the presence of various conditions. Nevertheless, evidence presented herein discourages the consideration of any mutagenic or carcino genic activity of vitamin C. In contrast, it substantiates a pro...
متن کاملVitamin C and COVID-19
Corona disease has killed at least 5 million people globally since it started in Wuhan, China in December 2019 (World Health Organization, 2021). The disease is caused by SARS-COVID-19, and is transmitted from person to person by respiratory droplets (Baladia et al., 2020, Ejaz et al., 2020). Although the early symptoms of COVID-19 include fever, weariness, headache, sore throat, cough, d...
متن کاملDiabetes and Glycohemoglobin
Introduction: Diabetes mellitus has long been recognized as a major cause of mortality and morbidity. The true frequency of the disorder is difficult to estimate because of differing diagnostic criteria but it is clearly the most common of the serious metabolic disorders occurring in roughly I to 4 percent of the U.S. population. It is a leading cause of mortality in this country, taking over 3...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2001
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/47.1.148